Matched FFPE tissue, plasma, & buffy coat sets
We collect and bank histology-confirmed plasma, buffy coat, serum, and whole blood specimens, anchored to pathologist-reviewed surgical tissue that confirms diagnosis, subtype, and staging — so liquid biopsy development starts with certainty, not assumptions.
Processed using gold-standard workflows and preserved under a never-thawed cold chain, our liquid biospecimens are built for performance, reliability, and downstream success.
Liquid biospecimens you can trust — handled with rigor, delivered with speed, and without unnecessary risk or complexity.
TRUSTED BY LEADING RESEARCH INSTITUTIONS
Quality-controlled
All tissues undergo a full review by our in-house pathology team and a nucleic acid extraction QC, ensuring that only well-preserved samples make it to your lab bench.
Fast delivery
By maintaining all inventory onsite in our lab, we offer rapid processing and next-day shipping on most orders, supporting your research without unnecessary delays.
Affordable
With pricing that’s often 50–75% lower than traditional suppliers, you never have to choose between quality and affordability. With us, you get both.
Large selection
Our comprehensive inventory spans tumor and normal tissue blocks from all major organs and cancer types, giving you broad access to the specimens you need.
Oncology, healthy, & benign blood products, at a glance
Reference Medicine offers oncology, benign, and healthy donor plasma, buffy coat, serum, and whole blood samples — delivered with verified quality, transparent data, and fast turnaround.
All oncology blood products are collected alongside surgical tissue that is reviewed by histopathology to confirm diagnosis, cancer subtype, and pathological stage. This ensures liquid biospecimens are anchored to verified clinical context—not inferred classifications.
Plasma, buffy coat, serum, and whole blood are processed using standardized, best-practice workflows designed to preserve molecular integrity. Plasma is double-spun to optimize cfDNA quality and reduce cellular contamination for downstream analysis.
Blood products are collected using a variety of industry-standard tubes commonly required for oncology research and assay development, including Streck, PAXgene, and K2 EDTA. This flexibility allows you to align specimen collection with validated workflows and downstream assay requirements.
All samples are frozen immediately after processing and maintained under continuous temperature monitoring. Specimens are never thawed prior to shipment, preserving integrity from collection through delivery to your lab.
In addition to oncology samples, we offer benign and healthy donor blood products to support control, baseline, and comparative studies. This enables assay development and validation without the need to source across multiple vendors.
Each blood product is delivered with structured clinical, pathologic, and collection metadata—including tube type and processing details. Clear documentation ensures samples are easy to interpret, compare, and integrate into your workflows.
When you source blood products from Reference Medicine, you get more than a vial — you get verified quality, transparent data, and unmatched turnaround time.
Hassle-free and simplified sample procurement from start to finish
We know that your time is precious, and we also know that your experiment can not be on hold for week or months (or dare we say it, ‘years!’) for specimens. That is why we do all the prep work for you, so we always have ready-to-ship, fit-for-purpose blood products ready to ship to your lab within days – less waiting, more science.
1. Review our Inventory
You can review and download current inventory, or you can ping us at hello@referencemedicine.com and we’ll get the latest listing right over to you. If you are looking for one of our pilot collections (i.e. longitudinal sets), these are not currently on the website, so please email us.
2. Request a quote
See specimens you would like to acquire? Simply send us an email or submit your request online and we’ll quickly build your order and get you a quote. Alternatively, you can send us specimen requirements and we are happy to help you navigate our inventory and make your selections.
3. Become a customer
Prior to transferring the specimens, we will need an agreement in place. To start this process, visit and complete our Customer Onboarding Form. In addition, feel free to connect us with your procurement team and we will work with them to get set up as a supplier in your system.
4. Place your order
To lock in your request, send us a Purchase Order or you can submit a signed quote. Once either of those are received, you’ll receive an emailed confirmation from us with our planned ship date and your shipping address. We will then ship whenever it is convenient for you!
Reference Medicine blood product offerings
HIGH STANDARDS OF COLLECTION, ANNOTATION, AND OUR DELIGHT GUARANTEE
Our plasma, buffy coats, serum and whole blood are collected under IRB and Ethics Committee-approved protocols from partner hospitals and labs.
All blood products we receive go through histologic confirmation, ensuring verified patient classification data, resulting in specimens you can trust
Your delight is always guaranteed! We stand by our products and time-tested techniques 100%. If there are any issues with your order, we will make it right - replace it, refund it, whatever it takes to ensure you're positively delighted.
Whether you’re validating across platforms or bridging one collection system to another, we can provide matched plasma by tube type, or even prospective collections in your preferred format.
We offer plasma in volumes up to 25 mL per patient, with matched buffy coats available from the same collection - giving you flexibility for both cancer specific and hereditary analysis from the same donor source.
Every plasma sample also undergoes visual and quantitative hemolysis scoring to ensure clarity and reliability. Samples exceeding our threshold are filtered out before they ever reach your lab.
Get in touch today to explore our current inventory of plasma, buffy coat, whole blood or serum samples.
Precision specimen collection workflows lead to the best results. We know.
We are more than just a specimen provider, we are your partner who works side-by-side with you to share knowledge so we can all do better science. From microtomy tips and validation cohort advice, to best practices for tissue grossing and preservation, we are here to support you every step of the way.
